Rabu, 12 April 2017

How Mechanism Summation of Multiple Stimuli in Skeletal Muscle



How Mechanism Summation of Multiple Stimuli in Skeletal Muscle

Five region when multiple stimuli
1. Treppe (Staircase Effect)
First few contractions demonstrate treppe. Even though the strength of contraction increased, relaxation was complete (temporal summation not responsible). Increase in tension may result from increased muscle warming and efficiency of enzymes.
2. Temporal Summation
After the first five stimuli, frequency was increased, which caused temporal summation. Resulted in a continual increase in tensions as one contraction was added to the previous contraction. Increase in tension may result from increased availability of intracellular calcium.
3. Incomplete Tetanus
4. Complete Tetanus
5. Fatigue



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